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The Economic and Social Council, in resolution 1186 (XLI) of 18 November 1966, took note with approval of the draft Protocol syrup promethazine with codeine transmitted the said addendum to the General Assembly. The General Assembly, in resolution 2198 (XXI) of 16 December 1966, took note of the Protocol and requested the Secretary-General "to transmit the text of the Protocol to the States mentioned in article V thereof, with a view to enabling them to accede to the Protocol.

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The resulting increase in transparency can create pressure on companies to reduce the pollution burden arising from their activities. It is the only legally binding international instrument on pollutant release and transfer registers. Its objective is "to enhance public access to information through the establishment of coherent, nationwide pollutant release and transfer registers (PRTRs). Although regulating information on pollution, rather than pollution directly, the Protocol is expected to exert a significant downward pressure on levels of pollution, as no company will want to be identified as among the biggest polluters.

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